Luke, Owen & Andrew Wilson

We all know Luke and Owen Wilson, especially from the greatest directorial debut, "Bottle Rocket" by Wes Anderson, but what about their brother, Andrew? The rugged Wilson was actually also in "Bottle Rocket" and has since been a small role actor in sexy films like "The Big Bounce" and "Charlie's Angels: Full Throttle."
Ashley, Mary Kate & Elizabeth Olsen

We grew up with "Full House," but the sister left out was Elizabeth Olsen, who we really didn't know much about until 2011's "Silent House." Since then, she's been the hot Olsen, on a roll with films like "Godzilla" and a big new role in the Marvel Universe, starting with "Avengers: Age of Ultron" as Scarlet Witch alongside sexy Scarlett Johansson.
Mark, Paul & Donnie Wahlberg

It's not that we don't recognize him as Mark's brother, but sometimes we just forget that Donnie Wahlberg exists, at least until A&E did that sibling show called "Wahlburgers" about chef Paul Wahlberg, with his brothers Mark and Donnie guest starring. Donnie has been around since the mid-'90s, focusing mainly on TV -- most recently "Blue Bloods" and "Boston's Finest" -- but he was also one of the lead roles in the early "Saw" films, you know, before "Saw" went from amazing to total crap.
John & Joan Cusack

Although John Cusack was a dreamboat in the days of "Say Anything ... ," his sister Joan has been a slow burn since the '80s, finding a perfect niche for herself on Showtime's "Shameless." Joan actually joined her brother, John, in "saying anything ... " back in 1989, one of her first major acting gigs.
Rob & Chad Lowe

Everyone knows the pretty blue-eyed Lowe celebrity who doesn't seem to age, but his younger brother, Chad, though lesser known, has been around acting since 1984, accruing more than 30 years of credits, including the original "Melrose Place, "ER," "Pretty Little Liars" most recently, and playing himself in the "Entourage" movie this last summer.
Joaquin, Rain, Summer & Liberty Phoenix

You may have known about brother, River, who passed away from an overdose at The Viper Room back in the early '90s, but Joaquin actually has three sisters, including Rain (pictured), who starred in briefly popular films like "Hitch" and "O" with Josh Hartnett, one of those '90s heartthrobs that are old as hell now. His sister, Liberty, did some brief TV acting in the '80s, but his other sister Summer has been quietly acting since the '80s, popping up as a guest star on "Growing Pains" and as both the "Fuck You Girl" in 1998's "The Faculty," also across from Josh Hartnett, and "SLC Punk!" in the same year.
Jeff & Beau Bridges

The Dude may be one of the most successful, gritty actors of his generations, but his old brother, Beau, who led the way with acting, is commonly forgotten despite his impressive rap sheet. Acting since the late '40s, Beau has been in countless TV movies and shows, most recently "Masters of Sex" and "The Millers."
David, Patricia, Rosanna, Richmond & Alexis Arquette

Everyone knows baby David and Patricia Arquette, but for those who don't recognize their older sister, Rosanna of "Ray Donovan" and "What About Brian" fame, might be missing out. Their eldest brother, Richmond, appeared in "Fight Club" and "Seven," a (film celebrating its 20th anniversary this year). Alexis Arquette is most famous for her gender reassignment, but also appeared in movies like "The Wedding Singer" and "Bride of Chucky" in the 1990s.
Warren Beatty & Shirley MacLaine

Did you know that the original Dick Tracy and Clyde of "Bonnie and Clyde" was brother to Shirley MacLaine? Both have been acting since about the same time in the 1950s, and both, despite being in their late 70s, continue to work today, albeit a bit less.
Charlie Sheen & Emilio Estevez

He's been big in the news, yet again, so one thing that is easily forgotten is Charlie Sheen's lineage ties to "The Mighty Ducks" Miracle Man, Emilio Estevez, with whom Sheen shares his father, Martin. Estevez forwent the name Sheen to conquer the entertainment industry on his own merits, although he has done passion projects of less commercial interest with his father.